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KMID : 0366919980100010341
Sungkyun Pharmceutical Journal
1998 Volume.10 No. 1 p.341 ~ p.348
Coffee Consumption During Pegnancy in Korean and Effect upon Serum Lipids Level in Maternal and Umbilical Cord Blood


Abstract
To investigate the effect of coffee consumption during pregnancy on serum lipids in maternal and infants¢¥ umbilical cord blood, 76 cases of newborn infants and women delivered of a child who had delivered at hospital located in Chung-Ju city from Feb. 1. 1996 to Aug. 31. 1996 were studied. The gestational ages of cases were 37 to 42 weeks and the average maternal ages were 28.3¡¾4.63 years old without any other medical or obstetric problems. Infants¢¥ Apgar scores and birth weights were decreased by above 3 cups per day of coffee consumption during pregnancy. No relationships between coffee consumption during pregnancy and maternal serum lipid levels were observed. However, serum total cholesterol and LDL-cholesterol levels in infants¢¥ umbilical cord were significantly increased with increasing coffee consumption during pregnancy. In contrary to coffee consumption, alcohol drinking habits affected maternal serum lipid levels but not serum lipid levels in infants¢¥ umbilical cord blood. Coffee consumption during pregnancy increased caffeine concentration in infants¢¥ umbilical cord blood. These results suggest that caffeine from maternal consumption of coffee can easily pass to the fetus and significantly affect serum lipids levels in infants¢¥ umbilical cord blood rather than those in maternal blood.
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